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Home Antibody All anti-ACTN2 antibodies

Anti-ACTN2 Antibody EP2530Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA303380 Rabbit monoclonal antibody against Alpha-Actinin 2 (EP2530Y ) 100ul $325 In Stock
LC420189 ACTN2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for ACTN2 (NM_001103)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human Alpha-Actinin 2 was used as an immunogen.
Clone NameEP2530Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:20,000; IHC: 1:100; IP: 1:40
Predicted MW Explanation 103 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens actinin, alpha 2 (ACTN2), transcript variant 1
Alternative NameCMD1AA
Database LinkNP_001094
Entrez Gene 88 Human
Entrez Gene 11472 Mouse
Entrez Gene 291245 Rat
FunctionAlpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq].
Related Pathway Focal adhesionAdherens junctionTight junctionLeukocyte transendothelial migrationRegulation of actin cytoskeletonSystemic lupus erythematosusMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Sarcomeric Alpha Actinin antibody [EP2530Y]; Anti-Sarcomeric Alpha Actinin antibody [EP2530Y] at 1/50000 dilution + human skeletal muscle lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 103 kDa.Observed band size : 103 kDa.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Sarcomeric Alpha Actinin antibody [EP2530Y]; TA303380 at 1/100 dilution staining Sarcomeric Alpha Actinin in human muscles by Immunohistochemistry, Paraffin-embedded tissue.


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