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Anti-ACTL6A Antibody EPR7443
Also for ACTL6A (NM_004301)
|A synthetic peptide corresponding to residues in human BAF53 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:50 - 1:100; ICC/IF: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens actin-like 6A (ACTL6A), transcript variant 1|
|ACTL6; Arp4; ARPN-BETA; BAF53A; INO80K|
Entrez Gene 86 Human
Entrez Gene 56456 Mouse
Entrez Gene 361925 Rat
|BAF53 is a family member of actin-related proteins (ARPs) that share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. BAF53 is a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate activation of specific proteins by antagonizing chromatin-mediated repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1 and the association of the BAF complex with chromatin/matrix (1).|
|Transcription FactorsDruggable Genome |
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Western blot - Anti-ACTL6A antibody [EPR7443]; All lanes : Anti-ACTL6A antibody [EPR7443] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : K562 cell lysate.Lane 3 : HeLa cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-Rabbit IgG at 1/2000 dilution.Predicted band size : 47 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACTL6A antibody [EPR7443]; Immunohistochemical analysis of paraffin embedded Human breast carcinoma tissue labelling ACTL6A with TA310170 at 1/50 dilution.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ACTL6A antibody [EPR7443]; Immunohistochemical analysis of paraffin embedded Human colon tissue labelling ACTL6A with TA310170 at 1/50 dilution.