Home Antibody All anti-ACTB antibodies
Also for ACTB (NM_001101)
|b-actin antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human b-actin.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||ELISA, WB: 0.5 - 2 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column (Protein A or G Sepharose)
|Homo sapiens actin, beta (ACTB)|
|Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism (reviewed in 1). The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging (2). beta actin is one of six different actin isoforms which have been identified. Like GAPDH, Β-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.|
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Western blot analysis of beta-actin in HeLa cell lysate with beta-actin antibody at (A) 0.5, (B) 1 and (C) 2 ug/mL.
Immunocytochemistry of beta-actin in HeLa cells with beta-actin antibody at 10ug/mL.