Home Antibody All anti-ACOT13 antibodies
Also for ACOT13 (NM_001160094)
|THEM2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THEM2.|
|Human, Mouse, Rat
||WB: 1 ug/ml, IHC: 2.5 ug/ml, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens acyl-CoA thioesterase 13 (ACOT13), transcript variant 2|
|HT012; PNAS-27; THEM2|
|THEM2, also known as ACOT13, belongs to the hotdog-fold superfamily and possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brain and has been shown to be co-localized with beta-tubulin on microtubules. THEM2 interacts with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids. At least two isoforms of THEM2 are known to exist.|
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Western blot analysis of THEM2 in HepG2 cell lysate with THEM2 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunohistochemistry of THEM2 in human liver tissue with THEM2 antibody at 2.5 ug/ml.