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Home Antibody All anti-ACIN1 antibodies

Anti-ACIN1 Antibody


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SKU Description Amount Price Availability*  
TA306020 Rabbit Polyclonal Acinus Antibody 100ug $325 3-7 Days
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OriGene Data

ImmunogenAcinus antibody was raised against a peptide corresponding to amino acids 775 to 789 of human AcinusL, 48 to 62 of human AcinusS’, or 17 to 31 of human AcinusS, which differ from those of mouse Acinus by one amino acid .
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens apoptotic chromatin condensation inducer 1 (ACIN1), transcript variant 2
Alternative NameACINUS; ACN; fSAP152
Database LinkNP_001158286
Entrez Gene 22985 Human
FunctionChromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE . A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS’ (2).
Related Pathway Spliceosome

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WB Image
Western blot analysis of Acinus in K562 whole cell lysate with Acinus antibody (IN) at 1 ug/mL.

IF Image
Immunofluorescence of Acinus in K562 cells with Acinus antibody at 20 ug/mL.

IF Image
Immunocytochemistry of Acinus in K562 cells with Acinus antibody at 5 ug/mL.


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