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Home All anti-ACACB antibodies
Anti-ACACB Phospho Antibody EPR3143Y
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for ACACB (NM_001093)
OriGene Data
| A synthetic peptide corresponding to residues surrounding serine 221 of human ACC2 was used as an immunogen. |
| EPR3143Y |
Rabbit IgG |
| Human |
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| WB, IHC |
ICC: 1:100, IHC: 1:100 - 250, IP: 1:10, WB: 1:2500 - 5000, |
| Store at -20C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens acetyl-CoA carboxylase beta (ACACB) |
| ACC2; ACCB; HACC275 |
| NP_001084 |
| Acetyl-CoA carboxylase 2 (ACC2) is a biotin-dependent enzyme that is involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. ACC2 is predominantly expressed in the heart, skeletal muscles and liver (1). It catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase and carboxyltransferase. ACC2 is throught to control fatty acid oxidation by the means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I (CPT-1), the rate-limiting step in fatty acid uptake and oxidation by mitochondria (2). The activity of ACC2 is controlled by reversible phosphorylation. Ser219 and Ser221 were found to be critical for the phosphorylation and subsequent inactivation of ACC2 (3). |
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* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on HeLa cell lysates using anti-Phospho-ACC2 (pS221) RabMAb .
IHC Image
Immunohistochemical analysis of paraffin-embedded human muscles using anti-ACACB RabMAb .
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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