OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-ACACA antibodies

Anti-ACACA Antibody EP687Y

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303374
  • Rabbit monoclonal antibody against Acetyl CoA Carboxylase 1 (ACC1)(EP687Y)
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)
IHC(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the human Acetyl-CoA carboxylase 1 was used as an immunogen.
Clone NameEP687Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:2000; IHC-P: Use at an assay dependent dilution
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IP.

Reference Data

Target NameHomo sapiens acetyl-CoA carboxylase alpha (ACACA), transcript variant 1
Alternative NameACAC; ACACAD; ACC; ACC1; ACCA
Database LinkNP_942131
Entrez Gene 31 Human
Entrez Gene 107476 Mouse
Entrez Gene 60581 Rat
FunctionAcetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq].
Related PathwayDruggable Genome Fatty acid biosynthesisPyruvate metabolismPropanoate metabolismMetabolic pathwaysInsulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Acetyl Coenzyme A Carboxylase antibody [EP687Y]; Anti-Acetyl Coenzyme A Carboxylase antibody [EP687Y] at 1/2000 dilution + A431 cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP labelled, at 1/2000 dilution.Predicted band size : 265 kDa.Observed band size : 265 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Acetyl Coenzyme A Carboxylase antibody [EP687Y]; Ab45174, at a dilution of 1/50, staining human Acetyl Coenzyme A Carboxylase in human liver by immunohistochemistry using paraffin embedded tissue.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title