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Anti-ABI2 Antibody EPR3906
Also for ABI2 (NM_005759)
|A synthetic peptide corresponding to residues in human Abi-2 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:500 - 1:1000
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt.
|Homo sapiens abl-interactor 2 (ABI2), transcript variant 3|
|ABI-2; ABI2B; AblBP3; AIP-1; argBP1; argBPIA; argBPIB; SSH3BP2|
Entrez Gene 10152 Human
Entrez Gene 329165 Mouse
Entrez Gene 286928 Rat
|Abl-interactor (Abi) proteins are targets of Abl-family nonreceptor tyrosine kinases and are required for Rac-dependent cytoskeletal reorganization in response to growth factor stimulation (1). Abi-2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases Abi-1 and/or Abi-2. This protein may be involved in cytoskeletal reorganization, and it regulates Abi-1/c-Abl-mediated phosphorylation of MENA (2).|
| Regulation of actin cytoskeleton|
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Western blot - Anti-ABI2 antibody [EPR3906]; .Performed under reducing conditions.Predicted band size : 57 kDa.Observed band size : 80 kDa .Exposure time : 2 minutes
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ABI2 antibody [EPR3906]; TA307196, at 1/250, staining ABI2 in paraffin-embedded Human brain tissue by Immunohistochemistry.
Immunocytochemistry/ Immunofluorescence - ABI2 antibody [EPR3906]; TA307196, at 1/500, staining ABI2 in HeLa cells by Immunofluorescence.