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Anti-ABI2 Antibody EPR3906


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against Abi-2(clone EPR3906)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401755) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Abi-2 was used as an immunogen.
Clone NameEPR3906 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:500 - 1:1000
Predicted MW Explanation 57 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens abl-interactor 2 (ABI2), transcript variant 3
Alternative NameABI-2; ABI2B; AblBP3; AIP-1; argBP1; argBPIA; argBPIB; SSH3BP2
Database LinkNP_005750
Entrez Gene 10152 Human
Entrez Gene 329165 Mouse
Entrez Gene 286928 Rat
FunctionAbl-interactor (Abi) proteins are targets of Abl-family nonreceptor tyrosine kinases and are required for Rac-dependent cytoskeletal reorganization in response to growth factor stimulation (1). Abi-2 may act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases Abi-1 and/or Abi-2. This protein may be involved in cytoskeletal reorganization, and it regulates Abi-1/c-Abl-mediated phosphorylation of MENA (2).
Related Pathway Regulation of actin cytoskeleton

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-ABI2 antibody [EPR3906]; .Performed under reducing conditions.Predicted band size : 57 kDa.Observed band size : 80 kDa .Exposure time : 2 minutes
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ABI2 antibody [EPR3906]; TA307196, at 1/250, staining ABI2 in paraffin-embedded Human brain tissue by Immunohistochemistry.
Immunocytochemistry/ Immunofluorescence - ABI2 antibody [EPR3906]; TA307196, at 1/500, staining ABI2 in HeLa cells by Immunofluorescence.


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