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Anti-ABCD1 TRUEMAB Antibody Clone OTI4E2
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for ABCD1 (NM_000033)
|Human recombinant protein fragment corresponding to amino acids 508-745 of human ABCD1 (NP_000024) produced in E.coli.|
|| WB 1:2000, IHC 1:150,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1)|
|ABC42; ALD; ALDP; AMN|
Entrez Gene 215 Human
|The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]. |
|Druggable Genome ABC transporters|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ABCD1 (RC206885, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ABCD1.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-ABCD1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA803204)