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Anti-ABCD1 Antibody EPR1362
Also for ABCD1 (NM_007435)
|A synthetic peptide corresponding to residues in mouse ABCD1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
|Does not react with Rat, Human. Is unsuitable for ICC/IF or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for ICC/IF or IP.
|Mus musculus ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1)|
|Ald; Aldgh; ALDP|
|Chemokines are a large family of small secreted proteins that regulate migration of white blood cells. Based on the arrangement of the first two of the four conserved cysteine residues, chemokines are classified into four subfamilies, CXC, CC, C and recently identified CX3C (1). The CC chemokines, in which the first 2 cysteines are adjacent, usually act on monocytes, T lymphocytes, and, in some cases, eosinophils, basophils, or mast cells. The CC subfamily proteins are 70 to 100 amino acids long, have 25 to 75% identity with each other, and include novel member of the CC chemokine subfamily, designated ABCD1 (SCYA22). The ABCD1 shares 28 to 34% identity with other CC chemokines and contains the characteristic 4-cysteine motif and 9 other highly conserved residues (2). The activated T cell-attracting CC chemokine CCL22 is expressed by stimulated B cells and mature dendritic cells (DC). Both identical and distinct proteins contribute to expression of CCL22 in DC and B cells (3).|
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Western blot - Anti-MDC antibody [EPR1362]; Anti-MDC antibody [EPR1362] at 1/1000 dilution + Recombinant full-length MDC protein at 0.005 µg.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 10 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MDC antibody [EPR1362]; ab124768, at 1/100, staining MDC in paraffin-embedded Mouse colon tissue by Immunohistochemistry.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MDC antibody [EPR1362]; ab124768, at 1/100, staining MDC in paraffin-embedded Mouse tonsil tissue by Immunohistochemistry.