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Home Antibody All anti-ABCD1 antibodies

Anti-ABCD1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305801
  • Goat Anti-ABCD1 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424967) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for ABCD1 (NM_000033)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-EDMQRKGYSEQD, from the internal region of the protein sequence according to NP_000024.2.
Clone Name IsotypeGoat IgG
Species ReactivityHuman Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1)
Alternative NameABC42; ALD; ALDP; AMN
Database LinkNP_000024
FunctionThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq].
Related Pathway

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WB Image
HEK293 overexpressing human ABCD1 and probed with TA305801 at 1ug/ml (mock transfection in first lane).

 

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