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Also for ABCC4 (NM_001105515)
| Peptide with sequence CNGQPSTLTIFETAL, from the C Terminus of the protein sequence according to NP_005836.2.|
|Test: Human, Rat. Expected from seq similarity: Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||ELISA: 1:64,000. WB: 1-3µg/ml. IHC: 2-4µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (ABCC4), transcript variant 2|
|MOAT-B; MOATB; MRP4|
Entrez Gene 10257 Human
Entrez Gene 239273 Mouse
Entrez Gene 170924 Rat
|The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq]. |
|Ion Channels: OtherTransmembraneDruggable Genome ABC transporters|
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TA302970 staining (0.5µg/ml) of rat renal cortex membranes (20µg total protein per lane). Detected by western blot using chemiluminescence. Data kindly provided by Dr. Antje Steinbach, Ernst-Moritz-Arndt University of Greifswald.
Figure from citation: Western blot analysis of protein expression of BCRP and four MRP family transporters by using anti-ABCG2, anti-ABCC1, anti-ABCC2, anti-ABCC3 and anti-ABCC4 antibody in HeLa and HeLa1A5 cells. View Citation
Figure from citation: Western blot analysis of human BCRP, MRP1, MRP3, MRP7 and UGT1A1 protein expression by using anti-ABCG2, anti-ABCC1, anti-ABCC3, anti-ABCC4 and anti-UGT1A1 antibody in various cell lines. View Citation
TA302970 (2.5µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.