Home Antibody All anti-ABCA3 antibodies
Anti-ABCA3 GAT Antibody Polyclonal
Generated by Genomic Immunization
Also for ABCA3 (NM_001089)
|DNA immunization. This antibody is specific for the N Terminus Region of the target protein.|
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:5000-1:20000; ELISA: 1:100-1:2000
|20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0|
|The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
|This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT
|Homo sapiens ATP-binding cassette, sub-family A (ABC1), member 3 (ABCA3)|
|ABC-C; ABC3; EST111653; LBM180; SMDP3|
|ABCA3 plays an important role in the formation of pulmonary surfactant, probably by transporting lipids such as cholesterol.Defects in ABCA3 are the cause of pulmonary surfactant metabolism dysfunction type 3 (SMDP3) [MIM:610921]; also called pulmonary alveolar proteinosis due to ABCA3 deficiency. A rare lung disorder due to impaired surfactant homeostasis. It is characterized by alveolar filling with floccular material that stains positive using the periodic acid-Schiff method and is derived from surfactant phospholipids and protein components. Excessive lipoproteins accumulation in the alveoli results in severe respiratory distress.|
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