OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right

Video overview of cDNA clone offering
Video brochure for cDNA clone
Related Products

Over 1000 citations of OriGene cDNA clones
Podocalyxin promotes glioblastoma multiforme cell invasion and proliferation by inhibiting angiotensin-(1-7)/Mas signaling Oncol. Rep. May 2015 [MAS1]

Suppressed expression of LDHB promotes pancreatic cancer progression via inducing glycolytic phenotype Med. Oncol. May 2015 [LDHB]

Biased Agonism as a Novel Strategy To Harness the Proresolving Properties of Melanocortin Receptors without Eliciting Melanogenic Effects J. Immunol. Apr 2015 [MC3R]

C5aR is frequently expressed in metastatic renal cell carcinoma and plays a crucial role in cell invasion via the ERK and PI3 kinase pathways Oncol. Rep. Apr 2015 [C5ar1]

View All Citations >>

 

CNR1 (NM_016083 ) Stable Cell Line

Catalog #:SL500066Price:$12888    technical questions?
Description:Human CB1 Cannabinoid Receptor Stable cell Line - CHO-K1
Gene:CNR1
Other names: CANN6; CB-R; CB1; CB1A; CB1K5; CB1R; CNR
Host CellCHO-K1
cDNA Clone:
Format:Cryopreserved cells, 6 x 10E6 cells/vial
Mycoplasma:Negative by MycoAlert Kit, Lonza
Cell Line Validation:Function assay
Background:The CB1 cannabinoid receptor is expressed primarily in the brain and is a target for cannabinoids (Matsuda et al., 1990, Gerard et al., 1991), the psychoactive ingredients of marijuana. When it is activated, the CB1 receptor inhibits adenylate cyclase through Gi protein. The CB1 receptors play a significant role in modulation of food intake.
Figure 1. CB1-mediated inhibition of intracellular cAMP accumulation. CHO-K1 cells that stably express the Flag tagged hCB1 Cannabinoid receptor (blue circles) were exposed to the indicated concentrations of WIN55212-2 for 30 min at 37°C along with 10uM forskolin and 1mM IBMX. Intracellular cAMP was assayed using the HitHunter Kit (GE Healthcare). Data points represent the average +/- standard deviation of duplicate determinations.

Related Products

 

patter
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title