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Over 1000 citations of OriGene cDNA clones
Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease Nat. Genet. Jan 2016 [TRAF6]

Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma Journal of the Neurological Sciences Jan 2016 [POSTN]

The New Role of CD163 in the Differentiation of Bone Marrow Stromal Cells into Vascular Endothelial-Like Cells Stem Cells International Jan 2016 [HMBOX1]

a-Helix-Peptides Composing the Human Nuclear Receptor ERR? Competitively Provoke Inhibition of Functional Homomeric Dimerization Biopolymers Dec 2015 [AR]

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IGF1R (NM_000875 ) Stable Cell Line

Catalog #:SL500005Price:$12888    technical questions?
Description:Human IGF-1 Receptor IGF1R Stable cell Line - Hep3B
Gene:IGF1R
Other names: CD221; IGFIR; IGFR; JTK13
Host CellHep3B
cDNA Clone:
Format:Cryopreserved cells, 4 x 10E6 cells/vial
Mycoplasma:Negative by MycoAlert Kit, Lonza
Cell Line Validation:Western blot
Background:The Insulin-like Growth Factor 1 Receptor (IGF1R), is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. IGF1R plays a critical role in transformation events. It is highly overexpressed in most malignant tissues especially in cancer tissues of breast, prostate, and lung, where it functions as an anti-apoptotic agent by enhancing cell survival.
Figure 1.Western blot analysis for Hep3B/IGF1R using mAb against human IGF1R. 15 ug of membrane protein was used for this Western blot analysis. Membrane protein concentration was measured by BCA kit (Thermo Scientific Inc.). Left lane: membrane protein from Hep3B/IGF1R stable cell line with the specific band around 81K of IGF1R. Right lane: membrane protein from Hep3B cells as negative control.

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