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Over 1000 citations of OriGene cDNA clones
Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue Sci Rep 2017 [GRIN2A]

Aesculin modulates bone metabolism by suppressing receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis and transduction signals Biochem. Biophys. Res. Commun. 2017 [TNFRSF11A]

A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5 J. Med. Chem. 2017 [CYP3A5]

Activation of Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonates Prodrugs by CYP1A1 as New Antimitotics Targeting Breast Cancer Cells J. Med. Chem. 2017 [CYP1A1]

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IGF1R (NM_000875 ) Stable Cell Line

Catalog #:SL500005Price:$12888    technical questions?
Description:Human IGF-1 Receptor IGF1R Stable cell Line - Hep3B
Gene:IGF1R
Other names: CD221; IGFIR; IGFR; JTK13
Host CellHep3B
cDNA Clone:
Format:Cryopreserved cells, 4 x 10E6 cells/vial
Mycoplasma:Negative by MycoAlert Kit, Lonza
Cell Line Validation:Western blot
Background:The Insulin-like Growth Factor 1 Receptor (IGF1R), is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. IGF1R plays a critical role in transformation events. It is highly overexpressed in most malignant tissues especially in cancer tissues of breast, prostate, and lung, where it functions as an anti-apoptotic agent by enhancing cell survival.
Figure 1.Western blot analysis for Hep3B/IGF1R using mAb against human IGF1R. 15 ug of membrane protein was used for this Western blot analysis. Membrane protein concentration was measured by BCA kit (Thermo Scientific Inc.). Left lane: membrane protein from Hep3B/IGF1R stable cell line with the specific band around 81K of IGF1R. Right lane: membrane protein from Hep3B cells as negative control.

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