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Over 1000 citations of OriGene cDNA clones
A new monoclonal antibody against human alpha-dystroglycan reveals reduced core protein in some, but not all, dystroglycanopathy patients Neuromuscular Disorders Sep 2014 [DAG1]

An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration Nat. Cell Biol. Sep 2014 []

Cell cycle restriction is more important than apoptosis induction for RASSF1A tumor suppression J. Biol. Chem. Sep 2014 [RASSF5]

Distinct Roles of Ape1 Protein, An Enzyme Involved in DNA Repair, in High or Low Linear Energy Transfer Ionizing Radiation-induced Cell Killing J. Biol. Chem. Sep 2014 [APEX1]

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IGF1R (NM_000875 ) Stable Cell Line

Catalog #:SL500005Price:$12888    technical questions?
Description:Human IGF-1 Receptor IGF1R Stable cell Line - Hep3B
Gene:IGF1R
Other names: CD221; IGFIR; IGFR; JTK13
Host CellHep3B
cDNA Clone:
Format:Cryopreserved cells, 4 x 10E6 cells/vial
Mycoplasma:Negative by MycoAlert Kit, Lonza
Cell Line Validation:Western blot
Background:The Insulin-like Growth Factor 1 Receptor (IGF1R), is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. IGF1R plays a critical role in transformation events. It is highly overexpressed in most malignant tissues especially in cancer tissues of breast, prostate, and lung, where it functions as an anti-apoptotic agent by enhancing cell survival.
Figure 1.Western blot analysis for Hep3B/IGF1R using mAb against human IGF1R. 15 ug of membrane protein was used for this Western blot analysis. Membrane protein concentration was measured by BCA kit (Thermo Scientific Inc.). Left lane: membrane protein from Hep3B/IGF1R stable cell line with the specific band around 81K of IGF1R. Right lane: membrane protein from Hep3B cells as negative control.

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