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Over 1000 citations of OriGene cDNA clones
Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p Cancer Lett. Nov 2015 [POU2F1]

OP9-Lhx2 stromal cells facilitate derivation of hematopoietic progenitors both in vitro and in vivo Stem Cell Research Sep 2015 [LHX2]

The presence of Estrogen Receptor ß modulates the response of breast cancer cells to therapeutic agents Int. J. Biochem. Cell Biol. Sep 2015 [ESR2]

A novel GLP-1 receptor interacting protein ATP6ap2 regulates insulin secretion in pancreatic beta cells J. Biol. Chem. Aug 2015 [ATP6AP2]

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IGF1R (NM_000875 ) Stable Cell Line

Catalog #:SL500005Price:$12888    technical questions?
Description:Human IGF-1 Receptor IGF1R Stable cell Line - Hep3B
Other names: CD221; IGFIR; IGFR; JTK13
Host CellHep3B
cDNA Clone:
Format:Cryopreserved cells, 4 x 10E6 cells/vial
Mycoplasma:Negative by MycoAlert Kit, Lonza
Cell Line Validation:Western blot
Background:The Insulin-like Growth Factor 1 Receptor (IGF1R), is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. IGF1R plays a critical role in transformation events. It is highly overexpressed in most malignant tissues especially in cancer tissues of breast, prostate, and lung, where it functions as an anti-apoptotic agent by enhancing cell survival.
Figure 1.Western blot analysis for Hep3B/IGF1R using mAb against human IGF1R. 15 ug of membrane protein was used for this Western blot analysis. Membrane protein concentration was measured by BCA kit (Thermo Scientific Inc.). Left lane: membrane protein from Hep3B/IGF1R stable cell line with the specific band around 81K of IGF1R. Right lane: membrane protein from Hep3B cells as negative control.

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