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Over 1000 citations of OriGene cDNA clones
Chimeric Proteins Combining Phosphatase and Cellulose-Binding Activities: Proof-of-Concept and Application in the Hydrolysis of Paraoxon Protein Pept. Lett. May 2014 [PON1]

POT1 loss-of-function variants predispose to familial melanoma Nat. Genet. 478-81 46 5. May 2014 [POT1]

18ß-Glycyrrhetinic Acid Suppresses Cell Proliferation through Inhibiting Thromboxane Synthase in Non-Small Cell Lung Cancer PLoS ONE e93690 9 4. April 2014 [TxAS]

A Bacteriophage Capsid Protein Provides a General Amyloid Interaction Motif (GAIM) That Binds and Remodels Misfolded Protein Assemblies J. Mol. Biol. April 2014 [SCNA]

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IGF1R (NM_000875 ) Stable Cell Line

Catalog #:SL500005Price:$12888    technical questions?
Description:Human IGF-1 Receptor IGF1R Stable cell Line - Hep3B
Gene:IGF1R
Other names: CD221; IGFIR; IGFR; JTK13
Host CellHep3B
cDNA Clone:
Format:Cryopreserved cells, 4 x 10E6 cells/vial
Mycoplasma:Negative by MycoAlert Kit, Lonza
Cell Line Validation:Western blot
Background:The Insulin-like Growth Factor 1 Receptor (IGF1R), is a transmembrane receptor that is activated by IGF-1 and by the related growth factor IGF-2. It belongs to the large class of tyrosine kinase receptors. IGF1R plays a critical role in transformation events. It is highly overexpressed in most malignant tissues especially in cancer tissues of breast, prostate, and lung, where it functions as an anti-apoptotic agent by enhancing cell survival.
Figure 1.Western blot analysis for Hep3B/IGF1R using mAb against human IGF1R. 15 ug of membrane protein was used for this Western blot analysis. Membrane protein concentration was measured by BCA kit (Thermo Scientific Inc.). Left lane: membrane protein from Hep3B/IGF1R stable cell line with the specific band around 81K of IGF1R. Right lane: membrane protein from Hep3B cells as negative control.

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