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Home cDNA Clone TrueORF All Txnrd1 ORF Clones

Txnrd1 (NM_031614) Rat cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RR210733L2 Lenti ORF clone of Txnrd1 (mGFP-tagged ORF) - Rat thioredoxin reductase 1 (Txnrd1), (10 ug), (Note: selenocysteine protein, Internal stop codon present. see reference data summary below), 10µg
$1070
4-5 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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TrueORF Data for RR210733L2
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Vector: pLenti-C-mGFP   Change vector? Tag: C-terminal mGFP
Sequence Data: ORF Nucleotide Sequence
ORF Size: 1500 bp
Predicted Protein MW: kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_031614.2, NP_113802
RefSeq Size: 3450 RefSeq ORF: 1500
Synonyms : Tr
LocusID: 58819 Cytogenetic: 7q13
Summary: This gene encodes a member of the family of pyridine nucleotide-disulfide oxidoreductases. This protein is a flavoenzyme, which uses NADPH for reduction of thioredoxins as well as other protein and nonprotein substrates, and plays a role in protection against oxidative stress. It contains a selenocysteine (Sec) residue, which is essential for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Jul 2008].

 

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