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Home cDNA Clone TrueORF All Cdc14a ORF Clones

Cdc14a (NM_001107718) Rat cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RR200085 Cdc14a (Myc-DDK-tagged ORF) - Rat CDC14 cell division cycle 14 homolog A (S. cerevisiae) (Cdc14a), transcript variant 2, (10 ug), 10µg   
$770
3-4 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
0 5 weeks
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Clone Modification
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The same insert cloned in Lenti and other vectors are also available.

Cat. No. Description Vector Price Availability  
RR200085L1 Lenti ORF clone of Cdc14a (Myc-DDK-tagged ORF) - Rat CDC14 cell division cycle 14 homolog A (S. cerevisiae) (Cdc14a), transcript variant 2, (10 ug)
$952 8 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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TrueORF Data for RR200085
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1881 bp
Predicted Protein MW: 70 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq Explanation: NM_001107718.2, NP_001101188 RefSeq Size: 2613 RefSeq ORF: 1881
Synonyms :
LocusID: 310806 Cytogenetic: 2q41
Gene Summary: The protein encoded by this gene is a dual-specificity phosphatase that preferentially dephosphorylates cyclin dependent kinase substrates to regulate the cell cycle. In human cell lines, this protein localizes to interphase chromosomes, and depletion of the transcript results in centrosome separation and cytokinesis defects. In mouse, the protein localizes to the nucleus of prophase I arrested oocytes and then becomes dispersed in meiotically competent oocytes. Knockdown of the protein delays exit from metaphase I and results in eggs with chromosomal abnormalities and elevated aneuploidy, demonstrating a function in regulation of meiosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015].

 

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