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OriGene in recent publications
Repurposing of Proton Pump Inhibitors as first identified small molecule inhibitors of endo-β-N-acetylglucosaminidase (ENGase) for the treatment of NGLY1 deficiency, a rare genetic disease Bioorg. Med. Chem. Lett. 2017 [ENGASE]

The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPARγ Life Sci. 2017 [OLR1]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [HSPA5]

Human GRP78 affinity towards its signaling partners Ire1α and PERK is differently modulated by an unfolded protein client Biochem. Biophys. Res. Commun. 2017 [ERN1]

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225 Categories

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NameCount
ABC transporters7
Acute myeloid leukemia87
Adherens junction117
Adipocytokine signaling pathway98
Adult stem cells133
Alanine, aspartate and glutamate metabolism44
Allograft rejection70
alpha-Linolenic acid metabolism13
Alzheimer's disease150
Amino sugar and nucleotide sugar metabolism57
Aminoacyl-tRNA biosynthesis30
Amyotrophic lateral sclerosis (ALS)73
Androgen and estrogen metabolism37
Antigen processing and presentation85
Apoptosis140
Arachidonic acid metabolism37
Arginine and proline metabolism68
Arrhythmogenic right ventricular cardiomyopathy (ARVC)54
Ascorbate and aldarate metabolism19
Asthma49
Autoimmune thyroid disease75
Axon guidance154
B cell receptor signaling pathway95
Basal cell carcinoma34
Basal transcription factors18
Base excision repair39
beta-Alanine metabolism29
Biosynthesis of unsaturated fatty acids9
Biotin metabolism2
Bladder cancer111
Butanoate metabolism33
C21-Steroid hormone metabolism13
Caffeine metabolism6
Calcium signaling pathway115
Cancer stem cells63
Cardiac muscle contraction56
Cell adhesion molecules (CAMs)150
Cell cycle138
Chemokine signaling pathway298
Chondroitin sulfate biosynthesis5
Chronic myeloid leukemia115
Circadian rhythm - mammal11
Citrate cycle (TCA cycle)54
Colorectal cancer131
Complement and coagulation cascades79
Cyanoamino acid metabolism4
Cysteine and methionine metabolism42
Cytokine-cytokine receptor interaction577
Cytosolic DNA-sensing pathway90
D-Arginine and D-ornithine metabolism1

 

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