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Home Recombinant Human Proteins All LEF1 Proteins

LEF1 (NM_016269) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP760177 Recombinant protein of human lymphoid enhancer-binding factor 1 (LEF1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug, 50ug (Larger pack size?) 199 In Stock
TA301292 Rabbit Monoclonal Antibody against LEF1 (Clone EPR2029Y) $325 In Stock
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Also for LEF1 (NM_016269)
cDNA Clone shRNA/siRNA Primer Pair Lysate Antibody

OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC208663, encoding human full-length LEF1
Tag:N-terminal HIS Predicted MW:44 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Protein Families: ES Cell Differentiation/IPSAdult stem cellsTranscription FactorsDruggable Genome
Protein Pathways: Wnt signaling pathwayAdherens junctionMelanogenesisPathways in cancerColorectal cancerEndometrial cancerMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_057353 RefSeq Size: 3084 RefSeq ORF: 1200
LocusID: 51176 Cytogenetic: 4q23  
Synonyms : LEF-1; TCF10; TCF1ALPHA; TCF7L3
Summary: This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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