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Home Recombinant Human Proteins All SHMT2 Proteins

SHMT2 (NM_005412) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP760127 Recombinant protein of human serine hydroxymethyltransferase 2 (mitochondrial) (SHMT2), nuclear gene encoding mitochondrial protein, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug, 50 ug (Larger pack size?) $199 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody (100 μL) $248 In Stock
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Also for SHMT2 (NM_005412)
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OriGene Data
Species:Human Expression Host:E.coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC204239, encoding human full-length SHMT2
Tag:N-terminal HIS Predicted MW:56
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Protein Pathways: Glycine, serine and threonine metabolismCyanoamino acid metabolismOne carbon pool by folateMethane metabolismMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_005403 RefSeq Size: 2113 RefSeq ORF: 1515
LocusID: 6472 Cytogenetic: 12q12  
Synonyms : GLYA; HEL-S-51e; SHMT
Summary: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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