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Home Recombinant Human Proteins All OSM Proteins

OSM (NM_020530) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP750016 Recombinant protein of human Oncostatin M (OSM) produced in E. coli., 50 ug (Larger pack size?) $399 In Stock
TA500195 anti-OSM (Oncostatin M) mouse monoclonal antibody, clone OTI2B6 (formerly 2B6) $379 In Stock
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC204277, encoding the region (Met25-Arg221) of human OSM
Tag:Tag-free Predicted MW:28.6 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: <0.1 EU per 1 µg of the protein by the LAL
Protein Families: Stem cell relevant signaling - DSL/Notch pathwayStem cell relevant signaling - JAK/STAT signaling pathwaySecreted ProteinES Cell Differentiation/IPSDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionJak-STAT signaling pathway
Protein Data
Protein Image

Reference Data
RefSeq: NP_065391 RefSeq Size: 1880 RefSeq ORF: 759
LocusID: 5008 Cytogenetic: 22q12.2  
Synonyms : MGC20461
Summary: This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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