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Home Recombinant Human Proteins All FGF2 Proteins

FGF2 (NM_002006) Purified Human Protein

Specifications Citations (1) Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP750002 Recombinant protein of human Fibroblast Growth Factor-basic (FGF2) produced in E. coli, 100 ug (Larger pack size?) 399 In Stock
TA500012 BFGF mouse monoclonal antibody, clone 3D9 $379 In Stock
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Also for FGF2 (NM_002006)
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC217426, encoding the region (Gly132-Ser288) of human FGF2
Tag:Tag-free Predicted MW:17.4 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a sterile solution containing 10 mM Tris.Cl, pH7.0, 150mM NaCl. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: <0.1 EU per 1 µg of the protein by the LAL
BioActivity: Measured in a cell proliferation assay using 3T3 cells. ED50 for this effect is typically 0.07-0.10 ng/ml.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: MAPK signaling pathwayRegulation of actin cytoskeletonPathways in cancerMelanoma
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001997 RefSeq Size: 6803 RefSeq ORF: 867
LocusID: 2247 Cytogenetic: 4q26  
Synonyms : BFGF; FGF-2; FGFB; HBGF-2
Summary: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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