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Home Recombinant Human Proteins All CCL11 Proteins

CCL11 (NM_002986) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP723802 Purified recombinant protein of Human chemokine (C-C motif) ligand 11 (CCL11 / Eotaxin), 10 ug (Larger pack size?) 199
$139
5 days
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
Human CCL11, the region of Gly24-Pro97, from gene Accession# NM_002986.2
Tag:Tag-free Predicted MW:8.4 kDa
Purity:>98%, as determined by Coomassie stained SDS-PAGE.
Concentration:Protein formulated and vialed at >50 ug/mL in specified buffer
Buffer:1 x PBS
Endotoxin: Less than 0.01 ng per µg protein as determined by the LAL method.
BioActivity: Bioactivity was measured by its property to chemoattract Baf3-hCCR3 transfectants in a dose dependent manner.
Protein Families: Secreted ProteinTransmembraneDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionChemokine signaling pathwayNOD-like receptor signaling pathwayAsthma
 

Reference Data
RefSeq: NP_002977 RefSeq Size: 925 RefSeq ORF: 291
LocusID: 6356 Cytogenetic: 17q12  
Synonyms : SCYA11; SCYA11
Summary: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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