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Home Recombinant Human Proteins All BMP2 Proteins

BMP2 (NM_001200) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP720011 Recombinant protein of human bone morphogenetic protein 2 (BMP2), the domain of Gln283-Arg396, 10 ug (Larger pack size?) $299 5 Days
TA316569 BMP2 Rabbit Polyclonal (aa86-102) Antibody $345 3-7 Days
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC214586, encoding the mature peptide (Gln283-Arg396) of human BMP2
Tag:Tag-free Predicted MW:13 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a 0.2 µM filtered solution of 50mM HAc. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: < 0.1 EU per µg protein as determined by LAL test
BioActivity: ED50 is less than 50 ng/ml as determined by the cytolysis of MC3T3-E1 cells. Specific Activity of 2.0 x 104 IU/mg
Protein Families: Stem cell relevant signaling - TGFb/BMP signaling pathwaySecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsEmbryonic stem cellsInduced pluripotent stem cellsDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionHedgehog signaling pathwayTGF-beta signaling pathwayPathways in cancerBasal cell carcinoma
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001191 RefSeq Size: 1547 RefSeq ORF: 1188
LocusID: 650 Cytogenetic: 20p12.3  
Synonyms : BDA2; BMP2A
Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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