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Home Recombinant Human Proteins All CTTN Proteins

CTTN (NM_138565) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP710315 Purified recombinant protein of Human cortactin (CTTN / EMS1), transcript variant 2, full length, with C-terminal DDK tag, expressed in sf9, 20ug, 20 ug (Larger pack size?) $399 In Stock
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OriGene Data
Species:Human Expression Host:Sf9 cells
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC201111, encoding human full-length CTTN
Tag:C-terminal DDK Predicted MW:57.3 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Protein Families: Druggable Genome
Protein Pathways: Tight junctionPathogenic Escherichia coli infection
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_612632 RefSeq Size: 3176 RefSeq ORF: 1539
LocusID: 2017 Cytogenetic: 11q13.3  
Synonyms : EMS1
Summary: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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