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Home Recombinant Human Proteins All ROBO1 Proteins

ROBO1 (NM_001145844) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP327713 Recombinant protein of human roundabout, axon guidance receptor, homolog 1 (Drosophila) (ROBO1), transcript variant 3, 20 ug (Larger pack size?) $680 In Stock
TA303077 Goat Polyclonal Antibody against ROBO1 $325 3-7 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC227713. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:175.7 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Axon guidance
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001139316 RefSeq Size: RefSeq ORF: 4818
LocusID: 6091 Cytogenetic: 3p12.3  
Synonyms : DUTT1; FLJ21882; MGC131599; MGC133277; SAX3; FLJ21882; MGC131599; MGC133277; SAX3; axon guidance receptor; roundabout 1; roundabout, axon guidance receptor, homolog 1 (Drosophila)
Summary: Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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