Promotion ends on May 1st.
Also for CYP27A1 (NM_000784)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC222953
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||56.9 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Primary bile acid biosynthesisMetabolic pathwaysPPAR signaling pathway
||RefSeq Size: 2059
||RefSeq ORF: 1596|
|Synonyms : CP27; CTX; CYP27|
|Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008]. |
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact firstname.lastname@example.org
for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich