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Home Recombinant Human Proteins All CYP7B1 Proteins

CYP7B1 (NM_004820) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP322647 Recombinant protein of human cytochrome P450, family 7, subfamily B, polypeptide 1 (CYP7B1), 20 ug (Larger pack size?) 680 In Stock
TA500050 Cyp7b1 mouse monoclonal antibody, clone 7E5 $379 In Stock
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Also for CYP7B1 (NM_004820)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC222647. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:58.1 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: TransmembraneP450Druggable Genome
Protein Pathways: Primary bile acid biosynthesis
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_004811 RefSeq Size: 2230 RefSeq ORF: 1521
LocusID: 9420 Cytogenetic: 8q21.3  
Synonyms : CBAS3; CP7B; SPG5A
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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