CPLX2 (NM_001008220) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC221947. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 15.2 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: Druggable Genome Protein Pathways:

Protein Data

RefSeq: NP_001008221	RefSeq Size: 4676	RefSeq ORF: 405
LocusID: 10814	Cytogenetic: 5q35.2
Synonyms : 921-L; CPX-2; CPX2; Hfb1
Summary: Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens complexin 2 (CPLX2), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human complexin 2 (CPLX2), transcript variant 2, mGFP tagged • GFP-tagged ORF clone of Homo sapiens complexin 2 (CPLX2), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human complexin 2 (CPLX2), transcript variant 2 , Myc-DDK-tagged • Myc-DDK-tagged ORF clone of Homo sapiens complexin 2 (CPLX2), transcript variant 2 as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of complexin 2 (CPLX2), transcript variant 2 Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • CPLX2 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • CPLX2 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Cplx2 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • CPLX2 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Cplx2 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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