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Home Recombinant Human Proteins All ENPP1 Proteins

ENPP1 (NM_006208) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP309222 Recombinant protein of human ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), 20 ug (Larger pack size?) 680
$398
In Stock
TA311356 Goat Anti-ENPP1 / PC1 Antibody $325 3-7 Days
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Also for ENPP1 (NM_006208)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC209222. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:99.8 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: TransmembraneDruggable Genome
Protein Pathways: Purine metabolismStarch and sucrose metabolismRiboflavin metabolismNicotinate and nicotinamide metabolismPantothenate and CoA biosynthesisMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_006199 RefSeq Size: 3493 RefSeq ORF: 2622
LocusID: 5167 Cytogenetic: 6q22  
Synonyms : ARHR2; COLED; M6S1; NPP1; NPPS; PC-1; PCA1; PDNP1
Summary: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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