Promotion ends on May 1st.
Also for PLCD1 (NM_006225)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC208263
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||85.5 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Inositol phosphate metabolismMetabolic pathwaysCalcium signaling pathwayPhosphatidylinositol signaling system
||RefSeq Size: 2707
||RefSeq ORF: 2271|
|Synonyms : NDNC3; PLC-III|
|Summary: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]. |
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**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich