CCR7 (NM_001838) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC206614. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 40.2 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: GPCRTransmembraneDruggable Genome Protein Pathways: Cytokine-cytokine receptor interactionChemokine signaling pathway

Protein Data

RefSeq: NP_001829	RefSeq Size: 2188	RefSeq ORF: 1137
LocusID: 1236	Cytogenetic: 17q12
Synonyms : BLR2; CD197; CDw197; CMKBR7; EBI1
Summary: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens chemokine (C-C motif) receptor 7 (CCR7) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens chemokine (C-C motif) receptor 7 (CCR7) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens chemokine (C-C motif) receptor 7 (CCR7) as 200 ug transfection-ready DNA Related Lysate from OriGene • Transient overexpression lysate of chemokine (C-C motif) receptor 7 (CCR7) Validated Antibodies • Rabbit Monoclonal antibody against CCR7/CKR7 (N-term) • Rabbit Monoclonal antibody against CCR7/CKR7 • Rabbit polyclonal anti-CCR7 antibody Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • CCR7 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • CCR7 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Ccr7 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • CCR7 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Ccr7 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene CCR7

If you would like OriGene Technologies to prepare a purified protein in the quantity of your own interest, simply fill out the form and click Submit. OriGene will contact you.

Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
* Quantity (µg)
Comments
* First Name
* Last Name
* Email Address
* Institution Name
* Country
* Phone