ABCG1 (NM_016818) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC206478. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 74 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: TransmembraneDruggable Genome Protein Pathways: ABC transporters

Protein Data

RefSeq: NP_058198	RefSeq Size: 2982	RefSeq ORF: 2001
LocusID: 9619	Cytogenetic: 21q22.3
Synonyms : ABC8; WHITE1
Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified. [provided by RefSeq, Jul 2008].

Researchers who bought this clone have also purchased:

Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1), transcript variant 2 as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1), transcript variant 2 as transfection-ready DNA • Lenti ORF clone of Human ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1), transcript variant 2, mGFP tagged • Lenti ORF clone of Human ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1), transcript variant 2 , Myc-DDK-tagged Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • ABCG1 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • ABCG1 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Abcg1 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • ABCG1 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Abcg1 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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