OriGene - MSH2 (NM_000251) Protein

Also for MSH2 (NM_000251)

OriGene Data

Species:	Human	Expression Host:	Human 293HEK cells
Expression cDNA Clone and Sequence	Recombinant protein was produced with TrueORF clone, RC205848. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:	C-terminal MYC/DDK	Predicted MW:	104.6 kDa
Purity:	> 80% as determined by SDS-PAGE and Coomassie blue staining
Mass Spec Validation:	This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology.
Concentration:	>50 ug/mL as determined by microplate BCA method
Buffer and Storage:	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Preparation:	Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families:	Stem cell - Pluripotency Druggable Genome
Protein Pathways:	Mismatch repair Pathways in cancer Colorectal cancer

Protein Data

Reference Data

RefSeq: NP_000242	RefSeq Size: 3145	RefSeq ORF: 2805
LocusID: 4436	Cytogenetic: 2p21
Synonyms : COCA1; FCC1; HNPCC; HNPCC1; LCFS2
Summary: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012].

*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information

**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

Cat. No.	Description	Datasheet	Price	Availability*
TP305848	Purified recombinant protein of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2), 20 ug (Larger pack size?)		$680	In Stock
TA50011-100	4C5, Anti-DDK monoclonal antibody (100 μL)		$248	In Stock

Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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MSH2 (NM_000251) Purified Human Protein