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Home Recombinant Human Proteins All PCK1 Proteins

PCK1 (NM_002591) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP304758 Recombinant protein of human phosphoenolpyruvate carboxykinase 1 (soluble) (PCK1), 20 µg (Larger pack size?) 680
$398
In Stock
TA319014 Rabbit polyclonal anti-PEPCK-C antibody $325 3-7 Days
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC204758. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:69 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Glycolysis / GluconeogenesisCitrate cycle (TCA cycle)Pyruvate metabolismMetabolic pathwaysPPAR signaling pathwayInsulin signaling pathwayMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_002582 RefSeq Size: 2688 RefSeq ORF: 1869
LocusID: 5105 Cytogenetic: 20q13.31  
Synonyms : PEPCK-C; PEPCK1; PEPCKC
Summary: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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