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Home Recombinant Human Proteins All PRKAB1 Proteins

PRKAB1 (NM_006253) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP303911 Recombinant protein of human protein kinase, AMP-activated, beta 1 non-catalytic subunit (PRKAB1), 20 ug (Larger pack size?) 680
$398
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Also for PRKAB1 (NM_006253)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC203911. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:30.2 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Insulin signaling pathwayAdipocytokine signaling pathwayHypertrophic cardiomyopathy (HCM)
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_006244 RefSeq Size: 2412 RefSeq ORF: 813
LocusID: 5564 Cytogenetic: 12q24.1  
Synonyms : AMPK; HAMPKb
Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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