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Home Recombinant Human Proteins All HSD17B8 Proteins

HSD17B8 (NM_014234) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP303806 Recombinant protein of human hydroxysteroid (17-beta) dehydrogenase 8 (HSD17B8), 20 ug (Larger pack size?) $680 2-3 Weeks
TA800574 HSD17B8 mouse monoclonal antibody, clone OTI6H2 (formerly 6H2) $379 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC203806. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:26.8 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Androgen and estrogen metabolismMetabolic pathways
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_055049 RefSeq Size: 989 RefSeq ORF: 786
LocusID: 7923 Cytogenetic: 6p21.3  
Synonyms : D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; KE6; RING2; SDR30C1
Summary: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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