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Home Recombinant Human Proteins All ATP6V0C Proteins

ATP6V0C (NM_001694) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP303652 Recombinant protein of human ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c (ATP6V0C), 20 µg (Larger pack size?) 680
$398
In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody $248 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC203652. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:15.6 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Transmembrane
Protein Pathways: Oxidative phosphorylationMetabolic pathwaysLysosomeVibrio cholerae infectionEpithelial cell signaling in Helicobacter pylori infection
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001685 RefSeq Size: 1126 RefSeq ORF: 468
LocusID: 527 Cytogenetic: 16p13.3  
Synonyms : ATP6C; ATP6L; ATPL; VATL; Vma3; VPPC
Summary: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. [provided by RefSeq, Nov 2010].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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