Promotion ends on May 1st.
Also for CAMKK2 (NM_172226)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC203468
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||59.4 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Protein KinaseTranscription FactorsDruggable Genome
||Adipocytokine signaling pathway
||RefSeq Size: 4923
||RefSeq ORF: 1626|
|Synonyms : CAMKK; CAMKKB|
|Summary: The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul |
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**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich