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Home Recombinant Human Proteins All SPHK2 Proteins

SPHK2 (NM_020126) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP303019 Recombinant protein of human sphingosine kinase 2 (SPHK2), 20 µg (Larger pack size?) 680 In Stock
TA315625 Rabbit polyclonal SPHK2 (Ab-614) antibody $325 3 Weeks
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC203019. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:69 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Sphingolipid metabolismMetabolic pathwaysCalcium signaling pathwayVEGF signaling pathwayFc gamma R-mediated phagocytosis
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_064511 RefSeq Size: 3012 RefSeq ORF: 1965
LocusID: 56848 Cytogenetic: 19q13.2  
Synonyms : SK 2; SK-2; SPK 2; SPK-2
Summary: This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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