Promotion ends on May 1st.
Also for ANAPC10 (NM_014885)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC202679
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||21.1 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Mass Spec Validation:
||This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology.
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Cell cycleOocyte meiosisUbiquitin mediated proteolysisProgesterone-mediated oocyte maturation
||RefSeq Size: 941
||RefSeq ORF: 558|
|Synonyms : APC10; DOC1|
|Summary: ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).[supplied by OMIM, Feb 2011]. |
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact firstname.lastname@example.org
for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich