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Home Recombinant Human Proteins All PCNA Proteins

PCNA (NM_002592) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP301741 Recombinant protein of human proliferating cell nuclear antigen (PCNA), transcript variant 1, 20 ug (Larger pack size?) $680 In Stock
TA800880 Mouse monoclonal anti-PCNA antibody, clone 4B2, Loading, clone OTI4B2 (formerly 4B2) $248 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC201741. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:28.6 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology.
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Stem cell - PluripotencyDruggable Genome
Protein Pathways: DNA replicationBase excision repairNucleotide excision repairMismatch repairCell cycle
Protein Data
Protein Image

Reference Data
RefSeq: NP_002583 RefSeq Size: 1355 RefSeq ORF: 786
LocusID: 5111 Cytogenetic: 20pter-p12  
Synonyms : ATLD2
Summary: The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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