Promotion ends on May 1st.
Also for HSD17B10 (NM_004493)
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC201734
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||25.8 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Valine, leucine and isoleucine degradationMetabolic pathwaysAlzheimer's disease
||RefSeq Size: 963
||RefSeq ORF: 786|
|Synonyms : 17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD;
|Summary: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]. |
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**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich