TNFRSF14 (NM_003820) Purified Human Protein

Species: Human Expression Host: Human 293HEK cells Expression cDNA Clone and Sequence Recombinant protein was produced with TrueORF clone, RC201167. Click on the TrueORF clone link to view cDNA and protein sequences. Tag: C-terminal MYC/DDK Predicted MW: 26.1 kDa Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology. Concentration: >50 ug/mL as determined by microplate BCA method Buffer and Storage: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions. Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. Protein Families: TransmembraneDruggable Genome Protein Pathways: Cytokine-cytokine receptor interaction

Protein Data

RefSeq: NP_003811	RefSeq Size: 1730	RefSeq ORF: 852
LocusID: 8764	Cytogenetic: 1p36.32
Synonyms : ATAR; CD270; HVEA; HVEM; LIGHTR; TR2
Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response. [provided by RefSeq, Jul 2008].

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Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14) as transfection-ready DNA • Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14) , Myc-DDK-tagged • Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14), mGFP tagged Related Lysate from OriGene • Transient overexpression lysate of tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) (TNFRSF14) Validated Antibodies • Purified Goat Polyclonal Antibody against HVEM / TR2 • Rabbit Polyclonal TNFRSF14 Antibody • Rabbit Polyclonal TNFRSF14 Antibody • TNFRSF14 / HVEM Rabbit Polyclonal (N-Terminus) Antibody • TNFRSF14 / HVEM Rabbit Polyclonal (C-Terminus) Antibody • Anti-HDAC4 Rabbit Polyclonal Antibody Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • TNFRSF14 - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • TNFRSF14 - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Tnfrsf14 - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • TNFRSF14 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Tnfrsf14 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related Primer Pair qSTAR qPCR primer pairs against Homo sapiens gene TNFRSF14

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Protein	Full Length Protein A domain of the protein Description of domain...
Tag	C-fusion N-fusion     Tag Description:
DNA or protein sequence of the final product
Preferred Expression Host	HEK293 E. coli Insect Cells Yeast
The main application with the purified protein	R&D reagent Cell-based Assay Animal Study Other, please specify:
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