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CTTN (NM_138565) Purified Human Protein

Specifications Citations (2) Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP301111 Recombinant protein of human cortactin (CTTN), transcript variant 2, 20 ug (Larger pack size?) $680 In Stock
TA310011 Rabbit anti-CTTN (Cortactin, Phospho-Tyr466) polyclonal antibody(Phospho-specific) $325 3 Weeks
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC201111. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:57.3 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Tight junctionPathogenic Escherichia coli infection
Protein Data
Protein Image

Reference Data
RefSeq: NP_612632 RefSeq Size: 3176 RefSeq ORF: 1542
LocusID: 2017 Cytogenetic: 11q13  
Synonyms : EMS1
Summary: This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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