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Home Recombinant Human Proteins All GLI1 Proteins

GLI1 (NM_005269) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP301110 Recombinant protein of human GLI family zinc finger 1 (GLI1), 20 µg (Larger pack size?) $680 In Stock
TA309673 Rabbit Polyclonal Gli1 Antibody $325 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC201110. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:117.7 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Stem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsEmbryonic stem cellsTranscription FactorsDruggable Genome
Protein Pathways: Hedgehog signaling pathwayPathways in cancerBasal cell carcinoma
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_005260 RefSeq Size: 3600 RefSeq ORF: 3321
LocusID: 2735 Cytogenetic: 12q13.2-q13.3  
Synonyms : GLI
Summary: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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