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IVD (NM_002225) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP301077 Recombinant protein of human isovaleryl Coenzyme A dehydrogenase (IVD), nuclear gene encoding mitochondrial protein, 20 ug (Larger pack size?) 680
In Stock
TA501742 anti-IVD mouse monoclonal antibody, clone OTI1B10 (formerly 1B10) $379 In Stock
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC201077. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:46.5 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Mass Spec Validation: This protein has been positively validated by MS/MS by Dr. Robert Moritz at The Institute of Systems Biology.
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Druggable Genome
Protein Pathways: Valine, leucine and isoleucine degradationMetabolic pathways
Protein Data
Protein Image

Reference Data
RefSeq: NP_002216 RefSeq Size: 2216 RefSeq ORF: 1272
LocusID: 3712 Cytogenetic: 15q14-q15  
Synonyms : ACAD2
Summary: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich


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