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Home Recombinant Human Proteins All TGFB1 Proteins

TGFB1 (NM_000660) Purified Human Protein

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Cat. No. Description Datasheet Price Availability*  
TP300973 Recombinant protein of human transforming growth factor, beta 1 (TGFB1), 20 ug (Larger pack size?) $680
$398
In Stock
TA506584 TGFB1 mouse monoclonal antibody,clone 2B5 $325 In Stock
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OriGene Data
Species:Human Expression Host:HEK293
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200973. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:28.4 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Secreted ProteinES Cell Differentiation/IPSTranscription FactorsDruggable Genome
Protein Pathways: MAPK signaling pathwayCytokine-cytokine receptor interactionCell cycleTGF-beta signaling pathwayPathways in cancerColorectal cancerMore Pathways >>
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_000651 RefSeq Size: 2346 RefSeq ORF: 1173
LocusID: 7040 Cytogenetic: 19q13.1  
Synonyms : CED; DPD1; LAP; TGFB; TGFbeta
Summary: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.[provided by RefSeq, Oct
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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