Promotion ends on May 1st.
|Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200614
. Click on the TrueORF clone link to view cDNA and protein sequences.
||Predicted MW:||50.2 kDa|
|Purity:||> 80% as determined by SDS-PAGE and Coomassie blue staining|
|Concentration:||>50 ug/mL as determined by microplate BCA method|
|Buffer:||25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.|
||Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
||Citrate cycle (TCA cycle)Metabolic pathwaysPathways in cancerRenal cell carcinoma
||RefSeq Size: 1791
||RefSeq ORF: 1533|
|Synonyms : HLRCC; LRCC; MCL; MCUL1|
|Summary: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul |
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact email@example.com
for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich