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Home Recombinant Human Proteins All CDK1 Proteins

CDK1 (NM_001786) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP300495 Recombinant protein of human cell division cycle 2, G1 to S and G2 to M (CDC2), transcript variant 1, 20 ug (Larger pack size?) 680 In Stock
TA316617 CDK1 / CDC2 Mouse Monoclonal (26E11) Antibody $345 In Stock
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Also for CDK1 (NM_001786)
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OriGene Data
Species:Human Expression Host:HEK293 cells
Expression cDNA Clone or AA Sequence
Recombinant protein was produced with TrueORF clone, RC200495. Click on the TrueORF clone link to view cDNA and protein sequences.
Tag:C-terminal MYC/DDK Predicted MW:33.9 kDa
Purity:> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
Protein Families: Protein KinaseStem cell - PluripotencyDruggable Genome
Protein Pathways: Cell cycleOocyte meiosisp53 signaling pathwayGap junctionProgesterone-mediated oocyte maturation
Protein Data
Protein Image
 

Reference Data
RefSeq: NP_001777 RefSeq Size: 1235 RefSeq ORF: 894
LocusID: 983 Cytogenetic: 10q21.1  
Synonyms : CDC2; CDC28A; P34CDC2
Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag® is a registered trademark of Sigma-Aldrich

 

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